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Metagenomic Microbiome Analysis Kit is a microbiota analysis kit using the most advanced sequencing process in the field: shotgun metagenomics.
It provides a complete profile of your intestinal bacteria and a detailed identification of microbial species and strains.
The kit is classified in our gastrointestinal health product category.
How to use our microbiota analysis kit
Once you have purchased your kit, the process takes place in a few simple steps:
- receive your sampling kit with your order
- note its identification number and keep it safe
- collect a stool sample easily and hygienically at home using the kit
- send the sample to our partner laboratory in France
- register your kit number in your customer area on our website, so that the sample can be tracked
- complete a detailed questionnaire, so that we can gather more information to help us interpret your results more accurately
- allow 8 to 12 weeks for the analysis once your sample has been received
- receive a detailed report (see sample report) once the analysis has been completed
- receive a product recommendation, in addition to this report, based on your results
Why analyse your intestinal microbiota?
Intestinal microbiota and dysbiosis: definitions
The intestinal microbiota refers to the billions of bacteria and other microorganisms found in the human intestine, which play an essential role in digestion, immunity and metabolic balance (1).
However, many people suffer from an imbalance in this ecosystem, known as dysbiosis (2).
Dysbiosis can result from a variety of causes (stress, medication, diet, environmental factors, etc.) and can manifest itself in subtle ways (digestive problems, fatigue, mood swings, skin problems, inflammation, etc.).
As it is difficult to identify dysbiosis on the basis of symptoms alone, which are often common to other disorders, the use of objective tests is particularly useful.
Purpose of an intestinal microorganism analysis test
Microbiological tests analyse the composition and diversity of bacterial species and other microorganisms present in the intestine, using stool samples (3).
They highlight key indicators such as:
- deficiencies in beneficial strains (e.g. lactobacilli, bifidobacteria, Akkermansia, etc.)
- proliferation of opportunistic or pathogenic species
- low microbial diversity, associated with certain disorders
- fermentation markers (gas production, short-chain fatty acid profile, etc.)
- the presence of species or yeasts linked to inflammation
- markers of intestinal permeability
Although the data obtained is not intended for medical use and does not replace a consultation with a health professional, it can serve as a basis, if necessary, for targeted interventions, such as adapting lifestyle habits, taking specific probiotics, etc.
4 key points and reasons to buy our metagenomic analysis kit
Metagenomic Microbiome Analysis Kit has 4 key strengths:
- shotgun metagenomics, the most advanced microbiological testing technology: unlike the usual tests based on 16S and targeting a single bacterial gene, our kit uses a latest-generation method known as shotgun metagenomics, which sequences all the microbial DNA (bacterial, fungal, viral, etc.) present in the sample. This ensures complete and accurate identification of your intestinal bacteria and microorganisms, both at species and strain level (4). This innovative technology also reveals the overall functioning of your microbiota (metabolic pathways, production of short-chain fatty acids, etc.). Please note that we only analyse the microbial DNA present in the stool, and never your human DNA;
- an analysis carried out by a certified French laboratory: your samples are processed according to strict quality standards by a certified French laboratory, with a level of reliability in line with clinical requirements;
- a complete solution with clear, usable and personalised results: once your analysis is complete, you will receive a detailed report (see sample report) containing a large number of clinically relevant indicators and offering concrete recommendations (diet, supplements, lifestyle), tailored to your profile;
- all in a practical, simple and hygienic kit: the sample is taken easily at home, thanks to secure and hygienic equipment and clear instructions. A return envelope is provided to ensure that the sample is sent back to the laboratory quickly and correctly (postage is free for France - for other countries, the customer must arrange for the sample to be returned).
Full instructions for our gut microbiota metagenomic test
What does this kit contain?
Our kit contains:
- 1 stool collection device
- 1 sterile swab
- 1 collection tube containing DNA stabilisation solution
- 1 airtight transport pouch
- 1 return envelope
- 1 document containing a unique identification number for recording and tracking the sample, and a QR code directing you to the full instructions below
When choosing your collection date, remember that it is recommended to post the sample from Sunday to Friday (and never the day before a bank holiday) and within 24 hours of collection.
Collecting the stool sample
1) Place the stool collection paper on the toilet seat.
IMPORTANT: avoid any contact between the sample and liquids (water, urine, bleach).
2) Open the lid of the tube containing the liquid, without spilling any. Place the tube on a flat surface. Remove the swab from its packaging.
3) Place the swab in the stool, holding it in the middle of the handle, and rotate it until the tip is well covered and no longer white.
IMPORTANT: Do not press on the end of the handle, as this will eject the tip.
4) Hold the swab over the tube, then press down on the end of the handle like a click pen, so that the stool-covered tip falls into the liquid. Then close the tube tightly. Do not mark any personal information on the tube (name, customer number, etc.).
5) Drop the stool collection paper down the toilet, then flush.
Sending the sample
6) Place the tube in the transport pouch.
7) Slide the bag containing the tube into the envelope.
8) Post the envelope within 24 hours of sampling. Outside France, return postage must be paid by the sender in accordance with local regulations.
Registering your kit number, online questionnaire and receiving your results
All that's left for you to do is register your kit number on our website via your customer area and complete a questionnaire to help us gather more information to better interpret your results.
8 to 12 weeks after receiving the sample, you will receive a detailed analysis report (see sample report) and our personalised product recommendation.
What is in Metagenomic Microbiome Analysis Kit
Any questions?
Our team of nutrition experts and scientists has the answers.
Your report will contain:
- your dominant enterotype (type of microbiota)
- an assessment of your microbial richness and diversity
- the quantification of 6 positive-impact bacteria (Akkermansia muciniphila, Bifidobacterium longum, Faecalibacterium prausnitzii) and 3 negative-impact bacteria
- the quantification of over 150 bacteria, depending on the diversity of your intestinal flora
- an analysis of the functional potential of your microbiota and the production of several compounds (short-chain fatty acids including butyrate, vitamins such as adenosylcobalamin, menaquinone, pantothenate and tetrahydrofolate, hydrogen sulphide, spermidine, histidine, GABA, tryptophan and tyrosine).
The best test for microbiota is the one that offers the greatest precision and depth of analysis.
Based on the analysis of a single bacterial gene, 16S tests offer an overview of the bacteria present, but remain limited in terms of the precise identification of species and strains, and do not provide any information about their functions.
Shotgun metagenomics, by sequencing all the microbial DNA, enables complete identification and functional analysis.
It is currently the reference method for in-depth assessment of the microbiota, used in our Metagenomic Microbiome Analysis Kit.
The results of your test will help you to see more clearly which food supplements, and more specifically which probiotics, are best suited to supporting your microbiota.
By default, we can recommend multi-strain formulas. This is because, in the absence of information on the microbiota, combining different species of ‘good bacteria’ covers a broader spectrum of actions and increases the chances of having beneficial effects (buy our bestselling probiotic Probio Forte, for example, which combines 5 different strains).
There are also probiotics with an even more extensive composition, combining 20 synergistic strains, for example (this is the case with the Full Spectrum Probiotic formula, which is also very popular).
A microbiota analysis may be carried out on the recommendation of a healthcare professional, particularly in the context of digestive disorders or a more in-depth assessment of intestinal health.
It is then carried out by a specialist laboratory, using a stool sample.
It is also possible to carry out this type of analysis independently by purchasing an online kit (ideally the Metagenomic Microbiome Analysis Kit, for the most complete and detailed results possible), taking the sample at home and sending it to the laboratory for analysis.
An unbalanced microbiota, characterised by a reduction in beneficial bacteria, a proliferation of opportunistic species and/or a change in their functions, can manifest itself as:
- persistent digestive problems (bloating, gas, diarrhoea, constipation, slow or difficult digestion, abdominal discomfort, etc.)
- unexplained fatigue
- food sensitivities or intolerances
- skin problems (blemishes, redness, etc.)
- and/or mood swings
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